产品说明
一般描述
PBX1 is a nuclear transcription factor that may regulate osteogenesis and skeletal patterning. Studies have reported that PBX1 modulates NANOG expression in human embryonic stem cells.
Rabbit Anti-PBX1 antibody recognizes canine, chicken, human, mouse, and rat PBX1.
免疫原
Synthetic peptide directed towards the N terminal region of human PBX1
应用
Rabbit Anti-PBX1 antibody can be used for western blot (0.25μg/ml) assays.
生化/生理作用
PBX1 binds the sequence 5′-ATCAATCAA-3′. It acts as a transcriptional activator of PF4 in complex with MEIS1. It may be converted into a potent transcriptional activator by the (1;19) translocation. It also may have a role in steroidogenesis and, subsequently, sexual development and differentiation.
序列
Synthetic peptide located within the following region: MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQI
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 47 kDa |
| species reactivity | human, mouse, bovine, rat, pig, dog |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_002576 |
| UniProt登记号 | P40424 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... PBX1(5087) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
