产品说明
一般描述
PRKCZ (protein kinase C ζ) is one of the PKC isozymes that belongs to protein kinase C family of serine/threonine kinases. It is located on human chromosome 1p36.
特异性
The antibody detects endogenous level of PKC zeta only when phosphorylated at threonine 560.
免疫原
Peptide sequence around phospho rylation site of threonine560(Q-L-T(p)-P-D) derived from Human PKC zeta .
生化/生理作用
PRKCZ (protein kinase C ζ) is essential to control asymmetric T-cell division. It modulates the functional phenotype of maturating CB (cord blood) T-cells. PRKCZ is required for the progression of Th1 (T-helper cells) cytokine producing cells. This protein participates in the regulation of several signalling processes like cell proliferation, cell survival and cell motility that are essential for cancer development and progression.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 80 kDa |
| species reactivity | human, mouse |
| 浓度 | 1.0 mg/mL |
| technique(s) | western blot: 1:500-1:1000 (Cell Lysate) |
| 同位素/亚型 | IgG |
| 登记号 | NP_001028753.1 |
| UniProt登记号 | Q05513 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... PRKCZ(5590) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
