产品说明
一般描述
PIGV codes for a mannosyltransferase enzyme that regulates glycosylphosphatidylinositol (GPI) synthesis. Mutations in this gene have been linked to hyperphosphatasia mental retardation (HPMR) syndrome.
Rabbit Anti-PIGV antibody recognizes human, mouse, rat, canine, and bovine PIGV.
免疫原
Synthetic peptide directed towards the N terminal region of human PIGV
应用
Rabbit Anti-PIGV antibody is suitable for western blot applications at a concentration of 1 μg/ml and for IHC using paraffin-embedded tissues at 4-8 μg/ml.
生化/生理作用
Glycosylphosphatidylinositol (GPI) is a complex glycolipid that anchors many proteins to the cell surface. The biosynthetic pathway of GPI is mediated by sequential addition of sugars and other components to phosphatidylinositol. PIGV adds the second mannose to the GPI core.
序列
Synthetic peptide located within the following region: FVDQLVEGLLGGLSHWDAEHFLFIAEHGYLYEHNFAFFPGFPLALLVGTE
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 56 kDa |
| species reactivity | dog, human, mouse, rabbit, guinea pig, rat, bovine |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_060307 |
| UniProt登记号 | Q9NUD9 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... PIGV(55650) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
