产品说明
一般描述
Polyamines are transcription factors that regulate cell proliferation and apoptosis. Polyamine modulated factor-1 (PMF-1) interacts with Nrf-2 and subsequently modulates SSAT gene transcription. Methylation of PMF1 has been linked to the progression of bladder cancer.
Rabbit Anti-PMF1 antibody recognizes bovine, human, mouse, rat, pig, and canine PMF1.
免疫原
Synthetic peptide directed towards the middle region of human PMF1
应用
Rabbit Anti-PMF1 antibody is suitable for use in western blot applications at a concentration of 2.5μg/ml.
生化/生理作用
PMF1 is part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. It may act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT.
序列
Synthetic peptide located within the following region: AAGSYQRFTDCYKCFYQLQPAMTQQIYDKFIAQLQTSIREEISDIKEEGN
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 23 kDa |
| species reactivity | human, goat |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_009152 |
| UniProt登记号 | Q6P1K2 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... PMF1(11243) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
