产品说明
一般描述
POLR2B is a subunit of RNA polymerase II that synthesises mRNA in cells. This subunit links DNA, nascent mRNA and the enzyme active site during transcription.
Rabbit Anti-POLR2B (AB1) antibody recognizes canine, bovine, human, mouse, rat, chicken, and pig POLR2B.
免疫原
Synthetic peptide directed towards the middle region of human POLR2B
应用
Anti-POLR2B (AB1) antibody has been used in immunoprecipitation and western blotting assays.
生化/生理作用
POLR2B encodes the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that maintains contact in the active site of the enzyme between the DNA template and the newly synthesized RNA.
序列
Synthetic peptide located within the following region: FFRSVFYRSYKEQESKKGFDQEEVFEKPTRETCQGMRHAIYDKLDDDGLI
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 134 kDa |
| species reactivity | human, rat, dog, horse, guinea pig, mouse, rabbit, bovine |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_000929 |
| UniProt登记号 | P30876 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... POLR2B(5431) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
