您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 品牌 > Sigma-Aldrich > Anti-PPA1 antibody produced in rabbit

Anti-PPA1 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV48396
规格纯度
IgG fraction of antiserum
参考价格
3311.54 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-PPA1 antibody produced in rabbit
Anti-MGC111556
Anti-Pyrophosphatase (inorganic) 1
Anti-SID6-8061
Anti-IOPPP
Anti-PP1
Anti-PP
产品介绍:

产品说明

一般描述

Pyrophosphatase (inorganic) 1 (PPA1) catalyzes the hydrolysis of pyrophosphate to inorganic phosphate in cells.
Rabbit Anti-PPA1 antibody recognizes bovine, human, mouse, and rat PPA1.
PPA1 (Inorganic pyrophosphatase 1) is a 32kDa protein consisting of an aspartate-rich region. It is expressed in all the tissues and mapped on chromosome 10.

免疫原

Synthetic peptide directed towards the N terminal region of human PPA1

应用

Rabbit Anti-PPA1 antibody is suitable for western blot applications at a concentration of 0.5mg-1mg/mL.

生化/生理作用

PPA1 (pyrophosphatase 1) facilitates hydrolytic conversion of pyrophosphate to orthophosphate. Study shows its tumor-specific protein expression in gastric cancer cells, thus, it has been suggested that PPA1 can be a potential tumor-specific marker in gastric cancers. PPA1 is also involved in the regulation of pancreatic ductal HCO3- secretion. It helps to organize transepithelial HCO3- prior to fluid secretion from human serous-like airway cells. In addition, it also controls anion exchanger (AE) activity by activating CFTR (cystic fibrosis transmembrane conductance regulator)/pendrin at the apical membrane and inhibiting the basolateral AE by cAMP agonists.

序列

Synthetic peptide located within the following region: PRWSNAKMEIATKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQT

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式IgG fraction of antiserum
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 33 kDa
species reactivitydog, rat, guinea pig, horse, mouse, rabbit, human, goat, bovine
浓度0.5 mg - 1 mg/mL
technique(s)western blot: suitable
NCBI登记号NP_066952
UniProt登记号Q15181
运输wet ice
储存温度−20℃
Gene Informationhuman ... PPA1(5464)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品