产品说明
一般描述
PRDM4 is a PR-domain containing protein that may be involved in cell differentiation and tumor suppression. Furthermore, PRDM4 is known to recruit protein arginine methyltransferase 5 (PRMT5) to modulate the proliferation and differentiation of neural stem cells.
Rabbit Anti-PRDM4 antibody recognizes canine, rabbit, human, mouse, and rat PRDM4.
免疫原
Synthetic peptide directed towards the C terminal region of human PRDM4
应用
Rabbit Anti-PRDM4 antibody can be used for western blot applications at a concentration of 1μg/ml.
生化/生理作用
PRDM4 is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. An elevated expression level of PRDM4 protein has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF).The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. An elevated expression level of this gene has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF). This gene is located in a chromosomal region that is thought to contain tumor suppressor genes.
序列
Synthetic peptide located within the following region: GPTSSSSAPEEEEEDDSEEEDLADSVGTEDCRINSAVYSADESLSAHK
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 88 kDa |
| species reactivity | human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_036538 |
| UniProt登记号 | Q9UKN5 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... PRDM4(11108) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
