产品说明
一般描述
Anti-RAB11FIP4 Antibody detects endogenous levels of total RAB11FIP4 protein.
RAB11FIP4 (RAB11 family interacting protein 4) belongs to the Rab11-FIPs family of Rab11 interacting proteins. Rab11-FIP4 is the sixth member of the Rab11-FIP family. It has an EF-hand calcium-binding motif. This gene is located on human chromosome 17q11.
免疫原
The antiserum was produced against synthesized peptide derived from human RAB11FIP4.
Immunogen Range: 452-501
生化/生理作用
Rab11-FIPs performs important activities like recycling of cargo to the membrane surface, transport of membrane to the cleavage furrow or midbody at the time of cell division and connecting Rab11 to molecular motor proteins. RAB11FIP4 (RAB11 family interacting protein 4) plays a major role in the membrane trafficking in association with cytokinesis. Overexpression of FIP4 results in poor prognosis and promotes tumor progression in pancreatic cancer.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 71 kDa |
| species reactivity | mouse, human |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: 1:40000 western blot: 1:500-1:1000 |
| NCBI登记号 | Q86YS3 |
| UniProt登记号 | Q86YS3 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... RAB11FIP4(84440) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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