Anti-RALYL antibody produced in rabbit

产品说明

一般描述

RNA binding protein-like (RALγL, NRPCL3, RALγ) is normally expressed in the preimplantation embryo, throughout development, and in all adult tissues examined. Raly interacts with splicing factors such as the alternative splicing factors RBFOX1 and RBFOX2. The expression of RALγ is coordinated with oxaliplatin resistance in colorectal cancers overexpressing the γB-1 protein.

特异性

Anti-RALγL polyclonal antibody reacts with bovine, human, and mouse RNA binding protein-like proteins.

免疫原

Synthetic peptide directed towards the C terminal region of human RALYL

应用

Anti-RALγL polyclonal antibody is used to tag RNA binding protein-like for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles RNA binding protein-like in mRNA splicing and cancer drug (oxaliplatin) resistance.

生化/生理作用

RALYL belongs to the RRM HNRPC family, RALY subfamily. It contains 1 RRM (RNA recognition motif) domain. The functions of RALYL remain unknown.

序列

Synthetic peptide located within the following region: AQKKQLEESLVLIQEECVSEIADHSTEEPAEGGPDADGEEMTDGIEEDFD

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

产品性质

安全信息