Anti-RAX (AB2) antibody produced in rabbit

产品说明

一般描述

Retina and anterior neural fold homeobox (RAX) is a paired-type homeobox gene expressed in the anterior neural fold and developing retina. RAX is involved in defining the eye field during early development wherein it participates in regulation of the proliferation and/or differentiation of retinal cells. Defects in RAX have been linked to the eye pathologies microphthalmia and anophthalmia.
Rabbit polyclonal anti-RAX (AB2) antibody reacts with bovine, canine, human, mouse, and rat retina and anterior neural fold homeobox factors.

免疫原

Synthetic peptide directed towards the N terminal region of human RAX

应用

Rabbit polyclonal anti-RAX (AB2) antibody is used to tag retina and anterior neural fold homeobox for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of retina and anterior neural fold homeobox in eye field/retinal development and eye pathologies such as microphthalmia and anophthalmia.
Rabbit Anti-RAX (AB2) antibody can be used for western blot assays at a concentration of 0.5μg/ml.

生化/生理作用

Retinal Homeobox Protein Rx (RAX) is a member of homeobox family of transcription factors. Mutations mouse and fish RAX lead to defects in retinal development and result in animal models of anophthalmia.

序列

Synthetic peptide located within the following region: MHLPGCAPAMADGSFSLAGHLLRSPGGSTSRLHSIEAILGFTKDDGILGT

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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