Anti-REXO4 antibody produced in rabbit

产品说明

一般描述

REX4, RNA exonuclease 4 homolog (S. cerevisiae) or REXO4 is a nucleolar protein that is involved in poly(A) RNA binding.
Rabbit Anti-REXO4 antibody recognizes human REXO4.

免疫原

Synthetic peptide directed towards the N terminal region of human REXO4

应用

Rabbit Anti-REXO4 antibody is suitable for western blot applications at a concentration of 1.25 μg/ml.

生化/生理作用

The regulation of the quinone reductase (QR) gene as well as other genes involved in detoxification is known to be mediated by an electrophile response element (EpRE). QR gene regulation by the antiestrogen-occupied estrogen receptor (ER) is mediated by the EpRE-containing region of the human QR gene, and the ER is one of the complex of proteins that binds to the EpRE. REXO4 directly binds to the EpRE and interacts with the ER. The activation of QR gene activity by REXO4 is enhanced in the presence of ER beta.

序列

Synthetic peptide located within the following region: MGKAKVPASKRAPSSPVAKPGPVKTLTRKKNKKKKRFWKSKAREVSKKPA

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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