产品说明

一般描述

RNF41 (E3 ubiquitin-protein ligase Nrdp1) is a ring-finger protein that associates with JAK2-associated cytokine receptor complexes. This ligase subsequently regulates the degradation and ectodomain shedding of type I cytokine receptors. RNF41 is also known to modulate the differentiation of hematopoietic progenitors.
Rabbit Anti-RNF41 antibody recognizes human, mouse, rat, canine, bovine, and zebrafish RNF41.

免疫原

Synthetic peptide directed towards the middle region of human RNF41

应用

Rabbit Anti-RNF41 antibody is suitable for western blot applications at 1 μg/ml.

生化/生理作用

RNF41 contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. The specific function of this protein has not yet been determined. The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. The specific function of this protein has not yet been determined. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.

序列

Synthetic peptide located within the following region: QQTRIAELEKTSAEHKHQLAEQKRDIQLLKAYMRAIRSVNPNLQNLEETI

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

产品性质

安全信息