产品说明
一般描述
SCNN1B codes for the beta subunit of the non-voltage-gated, sodium channel protein. SCNN1B has been implicated in Liddle′s syndrome.
Rabbit Anti-SCNN1B antibody recognizes human, canine, bovine, rat, mouse, and rabbit SCNN1B.
免疫原
Synthetic peptide directed towards the C terminal region of human SCNN1B
应用
Rabbit Anti-SCNN1B antibody is suitable for western blot applications at a concentration of 0.125 μg/ml.
生化/生理作用
When expressed in the bladder epithelium, the protein encoded by the SCNN1B gene might be implicated in the mechanosensory transduction in the bladder afferent pathways, thereby inducing detrusor instability by outlet obstruction. Common variants of this gene confer susceptibility to human essential hypertension.
序列
Synthetic peptide located within the following region: QPDTAPRSPNTGPYPSEQALPIPGTPPPNYDSLRLQPLDVIESDSEGDAI
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 70 kDa |
| species reactivity | pig, dog, human, goat, bovine |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_000327 |
| UniProt登记号 | P51168 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... SCNN1B(6338) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
