Anti-SFRS10 (AB2) antibody produced in rabbit

产品说明

一般描述

Transformer-2 protein homolog β/splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) (TRA2B, SFRS10) is an alternative splicing regulator that itself exists as alternative splice variants. Alternative mRNA splicing provides transcript diversity. SFRS10 binds SMN1/SMN2 RNA and restores full-length (FL)-SMN2 mRNA levels in vitro. Deficiency of SFRS10 results in early embryonic lethality.

特异性

Anti-SFRS10 (AB2) polyclonal antibody reacts with zebrafish, bovine, human, mouse, rat, canine, chicken, and pig transformer-2 protein homolog β/splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) proteins.

免疫原

Synthetic peptide directed towards the middle region of human SFRS10

应用

Anti-SFRS10 (AB2) polyclonal antibody is used to tag transformer-2 protein homolog β/splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of transformer-2 protein homolog β/splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) in the regulation of alternative pre-mRNA splicing.

生化/生理作用

SFRS10 contains 1 RRM (RNA recognition motif) domain and belongs to the splicing factor SR family. It is a sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing.

序列

Synthetic peptide located within the following region: GVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVD

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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