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Anti-SIRT2 (AB2) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV32385
规格纯度
affinity isolated antibody
参考价格
6305.78 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-SIRT2 (AB2) antibody produced in rabbit
Anti-Sirtuin (silent mating type information Regulation 2 homolog) 2 (S. cerevisiae)
产品介绍:

产品说明

一般描述

SIRT2 is an NAD+-dependent tubulin deacetylase that mainly occurs in the cytoplasm. SIRT2 has been implicated in mitotic exit during the cell cycle.
Rabbit Anti-SIRT2 (AB2) antibody recognizes bovine, zebrafish, human, mouse, rat, and pig SIRT2.

免疫原

Synthetic peptide directed towards the C terminal region of human SIRT2

应用

Rabbit Anti-SIRT2 antibody has been used for western blot assays. The antibody can be used at a concentration of 1.0μg/ml for immunoblots.

生化/生理作用

SIRT2 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT2 is included in class I of the sirtuin family. Two transcript variants result from alternative splicing of this gene.

序列

Synthetic peptide located within the following region: DVAWLGECDQGCLALAELLGWKKELEDLVRREHASIDAQSGAGVPNPSTS

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 40 kDa
species reactivityhuman
浓度0.5 mg - 1 mg/mL
technique(s)western blot: suitable
NCBI登记号NP_036369
UniProt登记号Q8IXJ6
运输wet ice
储存温度−20℃
Gene Informationhuman ... SIRT2(22933)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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