Anti-STAG3 antibody produced in rabbit

产品说明

一般描述

The protein encoded by STAG3 gene is expressed in the nucleus, specifically in testis and is a subunit of the cohesin complex which regulates the cohesion of sister chromatids during cell division. The gene has multiple pseudogenes. STAG3 is the only meiosis-specific subunit that is present within all four meiosis-specific cohesin complexes.

免疫原

Synthetic peptide directed towards the middle region of human STAG3

应用

Anti-STAG3 antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL.

生化/生理作用

STAG3 (Stromal antigen 3) gene encodes a meiosis-specific subunit of the cohesin complex that belongs to SCC3 family and is mapped on 7q22 region of chromosome 7. It facilitates the cohesion of sister chromatids after DNA replication during meiosis. STAG3 is expressed specifically in testis and loss of function mutation in the gene results in male infertility.

序列

Synthetic peptide located within the following region: VPHQVILPALTLVYFSILWTLTHISKSDASQKQLSSLRDRMVAFCELCQS

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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