Anti-SUNC1 antibody produced in rabbit

产品说明

免疫原

Synthetic peptide directed towards the C terminal region of human SUNC1

应用

Anti- SUNC1 antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL.

生化/生理作用

SUNC1 (Sad1 and UNC84 domain containing 1) or SUN3 gene encodes a 40.5kDa nuclear envelope protein, Sad1 and UNC84 domain containing 1, which is mapped on to chromosome 7. It is widely expressed in pancreatic islet cells as a partly granular cytoplasmic expression pattern. Expression of SUNC1 gene is used for detecting the genetic variants altering risk of amyotrophic lateral sclerosis (ALS) by using a two-stage genome-wide association study (GWAS). Mutation in nuclear envelope proteins leads to Charcot-Marie-Tooth disease, type 2B1 and spastin-associated hereditary spastic paraplegia.

序列

Synthetic peptide located within the following region: IKLATKIIPTAVTMEHISEKVSPSGNISSAPKEFSVYGITKKCEGEEIFL

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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