产品说明
免疫原
Synthetic peptide directed towards the C terminal of human SUV420H1.
生化/生理作用
Suv420h1 is a histone methyltransferase that specifically trimethylates ′Lys-20′ of histone H4. H4 ′Lys-20′ trimethylation represents a specific tag for epigenetic transcriptional repression. It mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins.
序列
Synthetic peptide located within the following region: FINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFC
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 35 kDa |
| species reactivity | rat, human, mouse, dog, bovine |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | ChIP: suitable western blot: suitable |
| NCBI登记号 | NM_001167884 |
| UniProt登记号 | Q3U8K7-4 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... KMT5B(51111) mouse ... Suv420h1(225888) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
