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Anti-TAF6 (AB2) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV34693
规格纯度
IgG fraction of antiserum
参考价格
3311.54 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-TAF6 (AB2) antibody produced in rabbit
Anti-TAFII85
Anti-TAF2E
Anti-TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80 kDa
Anti-TAFII70
Anti-MGC:8964
Anti-TAFII80
Anti-DKFZp781E21155
产品介绍:

产品说明

一般描述

TAF6 codes for a subunit of transcription factor IID (TFIID) that associates weakly with TATA-binding protein (TBP). However, TAF6 can interact strongly with TAF1.
Rabbit Anti-TAF6 antibody recognizes zebrafish, bovine, human, mouse, rat, and canine TAF6.

免疫原

Synthetic peptide directed towards the N terminal region of human TAF6

应用

Rabbit Anti-TAF6 antibody is suitable for western blot applications at a concentration of 1.25 μg/ml and for IHC (4-8 μg/ml).

生化/生理作用

TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF6 is one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1,the largest subunit of TFIID. One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Four isoforms have been identified but complete transcripts have been determined for only three isoforms. One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis.

序列

Synthetic peptide located within the following region: LTDEVSYRIKEIAQDALKFMHMGKRQKLTTSDIDYALKLKNVEPLYGFHA

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式IgG fraction of antiserum
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 71 kDa
species reactivityguinea pig, mouse, rat, bovine, dog, human, horse
浓度0.5 mg - 1 mg/mL
technique(s)immunohistochemistry: suitable
western blot: suitable
NCBI登记号NP_620834
UniProt登记号A4D2B3
运输wet ice
储存温度−20℃
Gene Informationhuman ... TAF6(6878)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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