产品说明
免疫原
Synthetic peptide directed towards the C terminal region of human TEX14
应用
Anti-TEX14 antibody produced in rabbit is suitable for western blotting at a concentration of 1μg/mL.
生化/生理作用
TEX14 (Testis expressed 14) gene encodes a protein that contains three ankyrin repeats, a protein kinase domain and a leucine zipper dimerization motif. The mRNA of the encoded protein is predominantly expressed in the testis. TEX14 is essential for intercellular bridge formation during meiosis as well as in mitosis it facilitates the kinetochore-microtubule attachment. TEX14 interacts with CEP55 and inhibits the GPPX3Y motifs of ALIX and TSG101 from interacting and confining to the midbody. Hence, TEX14 blocks the cell abscission and transform midbodies into intercellular bridges.
序列
Synthetic peptide located within the following region: ASSDTLVAVEKSYSTSSPIEEDFEGIQGAFAQPQVSGEEKFQMRKILGKN
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 160 kDa |
| species reactivity | human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_938207 |
| UniProt登记号 | Q8IWB6 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... TEX14(56155) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
