产品说明
一般描述
TRIM9 is a tripartite motif containing protein that functions as an E3 ubiquitin ligase in the cerebral cortex. It is also known to modulate ventral guidance via the UNC-6/UNC-40 pathway. Repression of TRIM9 has been linked to disorders such as dementia with Lewy bodies and Parkinson′s disease.
Rabbit Anti-TRIM9 antibody recognizes human TRIM9.
免疫原
Synthetic peptide directed towards the C terminal region of human TRIM9
应用
Rabbit Anti-TRIM9 antibody is suitable for western blot applications at a concentration of 0.5 μg/ml.
生化/生理作用
The protein encoded by TRIM9 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified.
序列
Synthetic peptide located within the following region: DGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEGKALQQYPSERELRGI
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 61 kDa |
| species reactivity | human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_443210 |
| UniProt登记号 | Q9C026-5 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... TRIM9(114088) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
