产品说明
一般描述
ZYX (Zyxin) is a phosphoprotein that associates with zinc. This phosphoprotein localizes at focal adhesion in the actin cytoskeleton and may regulate cytoskeletal organization.
Rabbit Anti-ZYX antibody recognizes bovine, human, mouse, and rat ZYX.
免疫原
Synthetic peptide directed towards the middle region of human ZYX
应用
Rabbit Anti-ZYX antibody can be used for western blot applications at a concentration of 1.25 μg/ml.
生化/生理作用
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles.
序列
Synthetic peptide located within the following region: GSPQPPSFTYAQQREKPRVQEKQHPVPPPAQNQNQVRSPGAPGPLTLKEV
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | IgG fraction of antiserum |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | 61 kDa |
species reactivity | human, horse |
浓度 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
NCBI登记号 | NP_003452 |
UniProt登记号 | Q15942 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... ZYX(7791) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich