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位置:首页 > 品牌 > Sigma-Aldrich > Cathepsin K (3F9) Mouse Monoclonal Antibody

Cathepsin K (3F9) Mouse Monoclonal Antibody

品牌
Sigma-Aldrich
货号
402M-1
包装型号
规格纯度
参考价格
2297.53 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Cathepsin K (3F9) Mouse Monoclonal Antibody
产品介绍:

产品说明

一般描述

Cathepsin K is a lysosomal papain–like cystine proteinase and can be expressed in normal osteoblasts, fibroblasts, and skin.1 Recently, cathepsin K has been reported as useful in distinguishing translocation renal cell carcinoma (RCC) from other subtypes of RCC.1 Mortignoni et al. tested 17 cases of translocation RCC and found that cathepsin K stained 6 of 8 cases of translocation RCC with t(X;1), all seven cases of translocation RCC with t(6;11), but was negative for one case with t(X;3) and one with t(X;17).1 Additionally, the study compared IHC detection of TFE3 antibody in the 17 cases and demonstrated that all translocation RCC with t(6;11) were completely negative for TFE3, but positive for cathepsin K; all other translocation RCC with different chromosomal tranlocations other than t(X;1) expressed TFE3.1 Thus, it is recommended that antibodies against both TFE3 and cathepsin K should be used for evaluating translocation renal cell carcinomas.1 None of the 305 other renal cell neoplasms representing the most common renal cell neoplasm subtypes were positive for cathepsin K.1 Zheng et al. reported only 2.7% of 1,140 carcinomas from various organs exhibited cathepsin K labeling, indicating that among carcinomas cathepsin K labeling is highly specific for translocation RCC and can be used to help differentiate translocation RCC from other carcinomas.2

质量


IVD

IVD

IVD

RUO

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.41

产品性质

质量水平500
100
生物来源mouse
偶联物unconjugated
抗体形式diluted ascites fluid
antibody product typeprimary antibodies
克隆3F9, monoclonal
描述For In Vitro Diagnostic Use in Select Regions (See Chart)
形式buffered aqueous solution
species reactivityhuman
包装vial of 0.1 mL concentrate (402M-14)
vial of 0.5 mL concentrate (402M-15)
bottle of 1.0 mL predilute (402M-17)
vial of 1.0 mL concentrate (402M-16)
bottle of 7.0 mL predilute (402M-18)
manufacturer/tradenameCell Marque
technique(s)immunohistochemistry: 1:25-1:100
同位素/亚型IgG2b
运输wet ice
储存温度2-8℃

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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