Glucagon (EP74) Rabbit Monoclonal Primary Antibody

产品说明

一般描述

The normal islets of Langerhans (pancreas) contain four major cell types, 15-20% of which are alpha cells which produce glucagon.¹ Alpha cell tumors can be divided into two distinct types; those associated with glucagonoma syndrome² (necrolytic migratory erythema, diabetes, anemia, stomatitis, weight loss, venous thromboses, diarrhea, and sometimes psychiatric disturbances), and those which are not. Those associated with the syndrome tend to be large and solitary and there is a high incidence of malignancy. Those glucagonomas not associated with the syndrome tend to be multiple and small and are nearly always benign.³ Immunohistochemically, the two types of glucagonomas are reactive to the glucagon antibody, though occasionally only weakly.

质量

IVD

IVD

IVD

RUO

联系

Glucagon Positive Control Slides, Product No. 259S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

制备说明

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其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of sigma-aldrich Co. LLC

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