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位置:首页 > 品牌 > Sigma-Aldrich > Claudin 1 Rabbit Polyclonal Antibody

Claudin 1 Rabbit Polyclonal Antibody

品牌
Sigma-Aldrich
货号
359A-1
包装型号
规格纯度
参考价格
1956.09 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Claudin 1 Rabbit Polyclonal Antibody
产品介绍:

产品说明

一般描述

The claudins are a family of over twenty proteins which are components of tight junctions. Tight junctions are specialized regions of cell-to-cell contact made up of a network of strands to act as a molecular ‘gasket′ for preventing the leakage of ions, water, etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. The claudins constitute a variable component, with specific claudins being associated with specific tissues. The immunoreactivity for anti-claudin 1 is membranous and is found in nearly all carcinomas. The staining is much stronger in the carcinoma cells than in normal tissues. Anti-claudin 1 in a panel of immunostains that includes antibodies against EMA (positive), S-100 (negative), and GLUT1 can be utilized as a robust marker in the diagnosis of perineurioma and neurofibroma. Some studies have shown anti-claudin 1 to be a specific marker for meningiomas. Therefore, anti-claudin 1 with anti-EMA, anti-S-100 protein, anti-CD34, and anti-glial fibrillary acidic protein (GFAP) may be helpful in the differentiation of meningiomas from histologic mimics.

质量


IVD

IVD

IVD

RUO

联系

Claudin 1 Positive Control Slides, Product No. 359S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

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其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平500
100
偶联物unconjugated
抗体形式Ig fraction of antiserum
antibody product typeprimary antibodies
克隆polyclonal
描述For In Vitro Diagnostic Use in Select Regions (See Chart)
形式buffered aqueous solution
species reactivityhuman
包装vial of 0.1 mL concentrate (359A-14)
vial of 0.5 mL concentrate (359A-15)
bottle of 1.0 mL predilute (359A-17)
vial of 1.0 mL concentrate (359A-16)
bottle of 7.0 mL predilute (359A-18)
manufacturer/tradenameCell Marque
technique(s)immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
控制colon carcinoma, neurofibroma
运输wet ice
储存温度2-8℃
可视化membranous

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

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