产品说明
一般描述
Inhibits Na+ and K+-dependent ATPases. Has cardiotonic properties.
Inhibits Na+,K+-ATPase. Exhibits cardiotonic properties. Preferentially enhances radiotoxicity in tumor cells and induces apoptosis by prolonging the irradiation-induced G2 delay.
包装
1 g in Glass bottle
生化/生理作用
Primary Target
Na+,K+-ATPase
Product does not compete with ATP.
Reversible: no
Cell permeable: no
警告
Toxicity: Toxic (F)
重悬
Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 2 weeks at 4°C or for up to 2 months at -20°C.
其他说明
Verheye-Dua, F.A., and Bohm, L. 2000. Strahlenther Onkol. 176, 186.
Hasenauer, J., et al. 1993. J. Biol. Chem.268, 3289.
Rakowski, F.F. 1993. J. Gen. Physiol.101, 117.
Mahaney, J.E., and Grisham, C.M. 1992. Biochemistry31, 2025.
Xu, Z.J., et al. 1992. J. Physiol.456, 405.
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C29H44O12 · 8H2O |
| 分子量 | 728.77 |
| MDL编号 | MFCD00149240 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥95% (HPLC) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze protect from light |
| 颜色 | white to off-white |
| 溶解性 | hot water: 10 mg/mL room-temperature water: insoluble |
| 运输 | ambient |
| 储存温度 | 2-8℃ |
| InChI | 1S/C29H44O12.8H2O/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31;;;;;;;;/h7,13,15-19,21-25,30-32,34-38H,3-6,8-12H2,1-2H3;8*1H2/t13?,15-,16+,17?,18+,19+,21+,22?,23?,24?,25?,26?,27?,28?,29?;;;;;;;;/m0......../s1 |
| InChI key | TYBARJRCFHUHSN-HMNHGHQSSA-N |
安全信息
| 象形图 |   |
| 警示用语： | Danger |
| 危险声明 | H300 - H331 - H373 |
| 预防措施声明 | P260 - P264 - P270 - P301 + P310 - P304 + P340 + P311 - P314 |
| 危险分类 | Acute Tox. 1 Oral - Acute Tox. 3 Inhalation - STOT RE 2 |
| 储存分类代码 | 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials |
| WGK | WGK 3 |
Sigma-Aldrich
m.cnreagent.com
