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Cathepsin K Substrate II, Fluorogenic-Calbiochem

品牌
Sigma-Aldrich
货号
219555
规格纯度
An internally quenched, highly cathepsin K-selective, fluorogenic peptide substrate that is efficiently cleaved by CatK (kcat/Km = 0.426 μM-1 S-1), but not by Cathepsins B/L/S/F/H/V.
参考价格
2732.28 *本价格含增值税费
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数量
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产品名称:
Cathepsin K Substrate II, Fluorogenic-Calbiochem
产品介绍:

产品说明

一般描述

An internally quenched, highly cathepsin K-selective, fluorogenic peptide substrate that is efficiently cleaved by CatK (kcat/Km = 0.426 µM-1 S-1), but not by Cathepsins B/L/S/F/H/V. Studies using WT and CatK-/- mice reveal that the substrate is not cleaved by other proteolytic enzymes present in fibroblast lysates. Emission Max: 420 NM, Excitation Max: 320 nM.


An internally quenched, highly cathepsin K-selective, fluorogenic peptide substrate that is efficiently cleaved by CatK (kcat/Km = 0.426 µM⁻¹ S⁻¹), but not by Cathepsins B/L/S/F/H/V.
An internally quenched, highly cathepsin K-selective, fluorogenic peptide substrate that is efficiently cleaved by CatK (kcat/Km = 0.426 µM-1 S-1), but not by Cathepsins B/L/S/F/H/V. Studies using WT and CatK-/- mice reveal that the substrate is not cleaved by other proteolytic enzymes present in fibroblast lysates.

包装

1 mg in Plastic ampoule
Packaged under inert gas

警告

Toxicity: Standard Handling (A)

序列

Abz-His-Pro-Gly~Gly-Pro-Gln-EDDnp

外形

Supplied as a trifluoroacetate salt.

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Lecaille, F., et al. 2003. Biochem. J.375, 307.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C40H50N14O12
分子量918.91

产品性质

质量水平100
测定≥95% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
desiccated
protect from light
颜色bright yellow
溶解性DMSO: 5 mg/mL
荧光λex 320 nm; λem 420 nm
运输wet ice
储存温度−20℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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