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1α-Hydroxyvitamin D3

品牌
Sigma-Aldrich
CAS
41294-56-8
货号
17946
包装型号
规格纯度
≥97.0% (HPLC)
参考价格
4608.42 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
41294-56-8
1α-Hydroxyvitamin D3
Alfacalcidol
1α-Hydroxycholecalciferol
产品介绍:

产品说明

一般描述

1α-Hydroxyvitamin D3, also known as alfacalcidol, is a synthetic vitamin D3 analogue, hydroxylated in position one. It is metabolized to 1,25-dihydroxycholecalciferol by 25-hydroxylases.

生化/生理作用

1α-Hydroxyvitamin D3 facilitates calcium absorption and deposition. It also has an ability to inhibit bone resorption and stimulate bone formation. Alfacalcidol is used for treating various bone diseases such as rickets/osteomalacia, renal osteodystrophy and osteoporosis. It acts as a chemopreventive agent and reduces the risk colitis and carcinogenesis.
Synthetic vitamin D3 analog that is metabolized to 1,25-dihydroxycholecalciferol. Inhibits bone resorption and stimulates bone formation. Supresses parathyroid hormone secretion by bovine parathyroid cells.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

基本信息

经验(实验)分子式C27H44O2
分子量400.64
EC 号255-297-1
MDL编号MFCD00868328
PubChem化学物质编号57647693
NACRESNA.79

产品性质

质量水平100
生物来源synthetic
测定≥97.0% (HPLC)
形式powder or crystals
颜色 white to off-white
储存温度−20℃
SMILES stringCC(C)CCC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C
InChI1S/C27H44O2/c1-18(2)8-6-9-19(3)24-13-14-25-21(10-7-15-27(24,25)5)11-12-22-16-23(28)17-26(29)20(22)4/h11-12,18-19,23-26,28-29H,4,6-10,13-17H2,1-3,5H3/b21-11+,22-12-/t19-,23-,24-,25+,26+,27-/m1/s1
InChI keyOFHCOWSQAMBJIW-AVJTYSNKSA-N
Gene Informationhuman ... VDR(7421)

安全信息

象形图GHS06
警示用语:Danger
危险声明H300
预防措施声明P301 + P330 + P331 + P310
危险分类Acute Tox. 1 Oral
储存分类代码6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

Sigma-Aldrich

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