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Anti-phospho-Retinoblastoma (pSer807,811) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
R6400
规格纯度
affinity isolated antibody, buffered aqueous glycerol solution
参考价格
9828.89 *本价格含增值税费
促销
服务
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数量
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产品名称:
Anti-phospho-Retinoblastoma (pSer807,811) antibody produced in rabbit
产品介绍:

产品说明

一般描述

RB1 (RB transcriptional corepressor 1) codes for nuclear phosphoprotein pRB (retinoblastoma protein). It is located on human chromosome 13q14. It is a tumor-suppressor gene.

特异性

Recognizes phosphorylated Rb (Ser807/Ser811) and does not react with non-phosphorylated Rb. Does not react with Rb phosphorylated at other sites.

免疫原

synthetic peptide corresponding to residues around phosphoserine 807/811 of the human retinoblastoma tumor suppressor protein (Rb), conjugated to KLH.

应用

Anti-phospho-Retinoblastoma (pSer807,811) has been used in western blotting.

生化/生理作用

RB1 (RB transcriptional corepressor 1) plays an important role throughout G1/S phase transition. Absence of RB induces prostate cancer metastasis. It plays an important role in modulating the cell cycle. It also regulates cell stemness and differentiation.

外形

Solution in 10 mM sodium HEPES, pH 7.5, containing 150 mM sodium chloride, 100 μg/ml bovine serum albumin and 50% glycerol.

制备说明

Purified using protein A and peptide affinity chromatography.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD02097167
NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous glycerol solution
species reactivitymouse, rat, human
technique(s)western blot (chemiluminescent): 1:1,000 using human fibroblasts synchronized by serum deprivation
UniProt登记号P06400
运输wet ice
储存温度−20℃
Gene Informationhuman ... RB1(5925)
mouse ... Rb1(19645)
rat ... Rb1(24708)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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