产品说明
一般描述
Src is a proto-oncogene that regulates neuronal functions, such as nerve cell differentiation. The Src kinase family structurally comprises of SH2, SH3 and kinase domains, as well as a negative regulatory C-terminal tail. Src has also been implicated in functions such as cell growth, development and cell-cell interactions . Anti-phospho-Src (pTyr529) antibody is specific for human, mouse, rat and chicken Src (60 kDa). The product has not been tested for reactivity with Fyn and Yes (92% homologous).
免疫原
The sequence is conserved in mouse, rat, chicken and frog.
synthetic phosphopeptide derived from the region of Src that contains tyrosine 529 based on the sequence of human src.
应用
Anti-phospho-Src (pTyr529) antibody is suitable for use in western blot (1:1,000 using human platelets or NIH3T3 cells). The product may also be used for immunoprecipitation (1:1000 using HEK293 or HEL cell lysates ) and and immunohistochemistry.
外形
Solution in Dulbecco′s phosphate-buffered saline (without Mg2+ and Ca2+), pH 7.3, containing 50% glycerol, 1.0 mg/ml BSA (IgG and protease-free) and 0.05% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
MDL编号 | MFCD03455769 |
NACRES | NA.44 |
产品性质
生物来源 | rabbit |
质量水平 | 200 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous glycerol solution |
species reactivity | human, mouse, rat, chicken |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable western blot: 1:1,000 using human platelets or NIH3T3 cells |
UniProt登记号 | P12931 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... SRC(6714) mouse ... Src(20779) rat ... Src(83805) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich