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位置:首页 > 品牌 > Sigma-Aldrich > Monoclonal Anti-Granzyme B antibody produced in mouse

Monoclonal Anti-Granzyme B antibody produced in mouse

品牌
Sigma-Aldrich
货号
G1044
规格纯度
clone GrB7, tissue culture supernatant
参考价格
7817.27 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Monoclonal Anti-Granzyme B antibody produced in mouse
产品介绍:

产品说明

特异性

Does not cross-react with granzyme A.

免疫原

recombinant human granzyme B.

应用

Monoclonal Anti-Granzyme B antibody is suitable for western blot and immunocytochemistry at a dilution of 1:20 using pretreated tissues.

生化/生理作用

Granzyme B, neutral serine protease, is expressed in cytoplasmic granules of activated cytotoxic T lymphocytes and natural killer cells. It contains a leader sequence (cleaved by a signal peptidase) and two amino acid prodomains (cleaved by the lysosomal cysteine protease DPPI). It plays a major role in the caspase dependent apoptotic pathway by activating most of the caspases in vitro and in vivo. It cleaves the aspartic acid residues, to facilitate cell death by various pathways. It has been shown that granzyme B has capacity to facilitate cytochrome C release from the mitochondria in a caspase independent way.

外形

Supplied in serum-free culture medium containing 1% bovine serum albumin and 0.1% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD01865484
NACRESNA.41

产品性质

质量水平200
生物来源mouse
偶联物unconjugated
抗体形式tissue culture supernatant
antibody product typeprimary antibodies
克隆GrB7, monoclonal
描述not suitable for immunocytochemistry (frozen sections)
分子量antigen 33 kDa
species reactivityhuman
technique(s)immunocytochemistry: 1:20 using pretreated tissues
western blot: suitable
UniProt登记号P10144
运输dry ice
储存温度−20℃
Gene Informationhuman ... GZMB(3002)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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