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p30

品牌
Sigma-Aldrich
CAS
3308-62-1
货号
P1246
包装型号
规格纯度
参考价格
5615.06 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
3308-62-1
p30
产品介绍:

产品说明

应用

p30 is an endogenous truncated form of p39 that associates with Cdk5 to form Nclk, which regulates neurotransmission, axon guidance, central nervous system (CNS) architecture, and pathogenesis. Therefore, p30 is useful in studying neurodegenerative diseases such as Alzheimer′s, Amyotrophic Lateral Sclerosis, and Parkinson′s Disease.

生化/生理作用

P30 activates GST-Neuronal cyclin-dependent kinase 5 (Cdk5). It also associates with Cdk5 to form an activated neuronal Cdc2-like kinase (Nclk). Product P1246 is recombinant, from bovine and is expressed in E. coli.

单位定义

One unit will incorporate 1 picomole of phosphate into histone H1 peptide per minute at pH 7.2 at 30 ℃.

外形

p30 is supplied in a solution of 25 mM Tris, pH 7.4, 1 mM DTT, and 30% glycerol. (0.5 μg protein/ 25 ul vial)

制备说明

Expressed as a GST fusion protein.

基本信息

MDL编号MFCD01727216
PubChem化学物质编号329820082
NACRESNA.54

产品性质

质量水平200
形式solution
储存温度−20℃
SMILES stringCl.CN(C)CCOc1ccc2OCCOc2c1
InChI1S/C12H17NO3.ClH/c1-13(2)5-6-14-10-3-4-11-12(9-10)16-8-7-15-11;/h3-4,9H,5-8H2,1-2H3;1H
InChI keyVRCSNYKNBODDIM-UHFFFAOYSA-N

Sigma-Aldrich

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