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PD 169316-CAS 152121-53-4-Calbiochem

品牌
Sigma-Aldrich
CAS
152121-53-4
货号
513030
规格纯度
A potent, cell-permeable, reversible, competitive, and selective p38 MAP kinase inhibitor (IC50 = 89 nM).
参考价格
2340.22 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
152121-53-4
PD 169316-CAS 152121-53-4-Calbiochem
4-(4-Fluorophenyl)-2-(4-nitrophenyl)-5-(4-pyridyl)-1H-imidazole
产品介绍:

产品说明

一般描述

A potent, cell-permeable, reversible, competitive, and selective p38 MAP kinase inhibitor (IC50 = 89 nM). Inhibition of p38 MAP kinase by PD 169316 blocks apoptosis induced by trophic factor withdrawal in non-neuronal and neuronal cell lines.
A potent, cell-permeable, reversible, competitive, and selective p38 MAP kinase inhibitor (IC50= 89 nM). Inhibition of p38 MAP kinase by PD 169316 blocks apoptosis induced by trophic factor withdrawal in non-neuronal and neuronal cell lines.

包装

1 mg in Plastic ampoule

生化/生理作用

Cell permeable: yes
Product competes with ATP.
Primary Target
p38 MAP kinase
Reversible: yes
Target IC50: 89 nM against p38 MAP kinase

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.

其他说明

Nath, R., et al. 2001. Cell Mol. Biol. Lett.6, 173.
Gallagher, T.F., et al. 1997. Bioorg. Med. Chem. 5, 49.
Kummer, J.L., et al. 1997. J. Biol. Chem. 272, 20490.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C20H13FN4O2
分子量360.34
MDL编号MFCD12405019

产品性质

质量水平100
测定≥98% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 orange-yellow
溶解性DMSO: 10 mg/mL
运输ambient
储存温度−20℃

安全信息

象形图GHS05GHS06
警示用语:Danger
危险声明H301 - H315 - H318 - H335
预防措施声明P261 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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