(Arg6, β-cyclohexyl-Ala8, D-Tic16, Arg17, Cys18)-Atrial Natriuretic Factor (6-18) amide (Cys7→Cys18 disulfide), TFA salt

产品名称：

132956-87-7
A71915 trifluoroacetate
(Arg6, β-cyclohexyl-Ala8, D-Tic16, Arg17, Cys18)-Atrial Natriuretic Factor (6-18) amide (Cys7→Cys18 disulfide), TFA salt
A-71915
[Arg6, Cha8]ANP-(6-15)-D-Tic-Arg-Cys-NH2 (Cys7→Cys18 disulfide), TFA salt
A 71915
Arg-Cys-β-cyclohexyl-Ala-Gly-Gly-Arg-Ile-Asp-Arg-Ile-D-Tic-Arg-Cys-NH2 (Cys2→Cys13 disulfide), TFA salt
RC-(Cha)-GGRIDRI-(D-Tic)-RC-NH2 (Cys2→Cys13 disulfide, TFA salt

产品介绍：

产品说明

生化/生理作用

A71915 is a potent atrial natriuretic peptide A (ANP, NPPA) receptor (NPR1, ANP-A, ANPR-A, NPR-A) antagonist (pK_i = 9.18 (K_i = 650 nM) by competitive binding against 300 nM rat ANP1-28 to human neuroblastoma NB-OK-1 cells; pA2 = 9.45 against rat ANP-induced cGMP production in NB-OK-1 cells). A71915 is reactive toward dog, human, mouse, rabbit, and rat species, and commonly employed both in cultures (1-10 μM) and in vivo for studying NPR-A-mediated responses.

基本信息

经验(实验)分子式	C₆₉H₁₁₆N₂₆O₁₅S₂ · xC₂HF₃O₂
分子量	1613.95 (free base basis)

产品性质

质量水平	100
测定	≥95% (HPLC)
形式	powder
颜色	white to off-white
储存温度	−20℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable