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Spectinomycin

品牌
Sigma-Aldrich
货号
S0692
规格纯度
Ready Made Solution, 100 mg/mL in DMSO/H2O, 1:1
参考价格
639.32 *本价格含增值税费
促销
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数量
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产品名称:
Spectinomycin
产品介绍:

产品说明

一般描述

Chemical structure: aminoglycoside

应用

Spectinomycin is an aminocyclitol antibiotic derived from Streptomyces spectabilis. It has been shown to have a wide variety of uses, including treating acute gonorrheal urethritis and cervictis, to mark cell layers to monitor cell fate during leaf development, as a selection marker in plant related transformation systems for plant cells containing the marker gene Spcr, to study respiratory tract infections of cattle caused by Pasteurella multocida and Mannheimia haemolytica, and to generate plants deficient for the plastid-encoded RNA polymerase on MS-agar media. Spectinomycin also has use in amplification of low copy number plasmid carrying replicons. It is recommended for use in cell culture applications at 7.5-20 mg/L.

包装

1 mL in glass bottle

生化/生理作用

作用方式:通过干扰肽基 tRNA 的转位抑制蛋白质合成(延伸)。
抗菌谱:革兰氏阴性和革兰氏阳性菌(仅包括淋球菌)。
抗性机理:rpsE(核糖体蛋白 S5 的基因)的突变可阻止壮观霉素的结合。

注意

Solutions can be stored at 2-8℃ for several weeks or at -20℃ for more extended periods.

制备说明

Stock solutions should be prepared at 10 mg/mL in water and 0.2 μm filtered.

其他说明

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Store under inert gas

基本信息

MDL编号MFCD04041129
NACRESNA.85

产品性质

质量水平200
生物来源Streptomyces sp.
形式solution
储存条件 (Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.Store under inert gas.)
浓度100 mg/mL in DMSO/H2O, 1:1
颜色 colorless
溶解性DMSO/H2O, 1:1: soluble 100 mg/mL
作用机制protein synthesis | interferes
抗生素抗菌谱Gram-negative bacteria
Gram-positive bacteria
mycobacteria
运输wet ice
储存温度−20℃

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 2
闪点(F)201.0 °F - closed cup
闪点(C)93.9 ℃ - closed cup
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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