产品说明
生化/生理作用
Capecitabine is an anti-cancer drug, a prodrug of doxifluridine, metabolized to 5-fluorouracil at the tumor site. The activation of capecitabine follows a pathway with three enzymatic steps and two intermediary metabolites, 5′-Deoxy-5-fluorocytidine (5′-DFCR) and 5′-Deoxy-5-fluorouridine (5′-DFUR), to form 5-fluorouracil.
Capecitabine is a fluoropyrimidine carbamate that undergoes preferential conversion to 5-fluorouracil in cancerous tissues.
基本信息
| 经验(实验)分子式 | C15H22FN3O6 |
| 分子量 | 359.35 |
产品性质
| 形式 | DMSO solution |
| 质量水平 | 200 |
| 浓度 | 10 mg/mL in DMSO |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| InChI | 1S/C15H22FN3O6/c1-3-4-5-6-24-15(23)18-12-9(16)7-19(14(22)17-12)13-11(21)10(20)8(2)25-13/h7-8,10-11,13,20-21H,3-6H2,1-2H3,(H,17,18,22,23)/t8-,10-,11-,13-/m1/s1 |
| InChI key | GAGWJHPBXLXJQN-UORFTKCHSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Danger |
| 危险声明 | H350 - H360FD |
| 预防措施声明 | P201 - P308 + P313 |
| 危险分类 | Carc. 1B - Repr. 1B |
| 储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
| 闪点(F) | 188.6 °F |
| 闪点(C) | 87 ℃ |
Sigma-Aldrich
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