产品说明
一般描述
Chemical structure: fluoroquinolone
应用
Ofloxacin is a synthetic fluoroquinolone with broad-spectrum antibacterial activity. It is a nalidixic acid analog. It is given to patients before undergoing retinal reattachment surgery.
包装
1, 10 g in poly bottle
生化/生理作用
Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, which haults DNA replication and cell division. Ofloxacin has been shown to convert LytA from the inactive E-form to the active C-form. It is a chiral molecule that inhibits pneumococcal cell wall-degrading virulence factors.
其他说明
Keep container tightly closed in a dry and well-ventilated place.
基本信息
| 经验(实验)分子式 | C18H20FN3O4 |
| 分子量 | 361.37 |
| MDL编号 | MFCD00226105 |
| PubChem化学物质编号 | 24278613 |
产品性质
| 质量水平 | 200 |
| 生物来源 | synthetic |
| 测定 | ≥99% (HPLC) |
| 形式 | powder |
| 溶解性 | 1 M NaOH: soluble 50 mg/mL |
| 作用机制 | DNA synthesis | interferes enzyme | inhibits |
| 抗生素抗菌谱 | Gram-negative bacteria Gram-positive bacteria mycobacteria |
| 储存温度 | 2-8℃ |
| InChI | 1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25) |
| InChI key | GSDSWSVVBLHKDQ-UHFFFAOYSA-N |
| Gene Information | human ... CSNK2A1(1457), KCNH1(3756) rat ... Gabra1(29705) |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
