产品说明
一般描述
(R)-FTY720-OMe is a structural analogue of FTY720 which acts as a specific competitive inhibitor of sphingosine kinase 2 (SK2). Furthermore, (R)-FTY720-OMe does not inhibit sphingosine kinase 1 (SK1) activity.
(R)-FTY720-OMe is the analogue of FTY720.
生化/生理作用
(R)-FTY720-OMe helps to block DNA synthesis and actin rearrangement induced by sphingosine 1-phosphate (S1P) in MCF-7 breast cancer cells. It can also reduce sphingosine kinase 2 (SK2) expression and prevent DNA synthesis in HEK 293 cells. (R)-FTY720-OMe has anti-breast cancer potential.
包装
5 mL Amber Glass Screw Cap Vial (857392O-1mg)
基本信息
经验(实验)分子式 | C20H35NO2 |
分子量 | 321.50 |
NACRES | NA.25 |
产品性质
测定 | >99% (TLC) |
包装 | pkg of 1 × 1 mg (857392O-1mg) |
manufacturer/tradename | Avanti Polar Lipids 857392O |
运输 | dry ice |
储存温度 | −20℃ |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
Sigma-Aldrich