产品说明
一般描述
A potent, cell-permeable, and irreversible inhibitor of caspase-5. Strongly inhibits caspase-1. Also inhibits caspase-4 and caspase-8.
A potent, cell-permeable and irreversible inhibitor of caspase-5 (ICErel-III, TY), as well as caspase-1 and caspase-4.
包装
1 mg in Plastic ampoule
生化/生理作用
Cell permeable: yes
Primary Target
caspase-1, caspase-4, caspase-5, caspase-8
Reversible: no
警告
Toxicity: Standard Handling (A)
序列
Z-Trp-Glu(OMe)-His-Asp(OMe)-CH₂F*
外形
Supplied as a trifluoroacetate salt.
重悬
Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
分析说明
single spot by TLC
其他说明
Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Rano, T., et al. 1997. Chem. Biol. 4, 149.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C37H42FN7O10 |
| 分子量 | 763.77 |
产品性质
| 质量水平 | 100 |
| 形式 | solid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze desiccated |
| 颜色 | white |
| 溶解性 | DMSO: 5 mg/mL |
| 运输 | ambient |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
