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位置:首页 > 品牌 > Sigma-Aldrich > 1H-苯并三唑-1-基氧三吡咯烷基六氟磷酸盐

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate

1H-苯并三唑-1-基氧三吡咯烷基六氟磷酸盐

品牌
Sigma-Aldrich
CAS
128625-52-5
货号
12805
规格纯度
purum, ≥97.0% (TLC)
参考价格
718.04 *本价格含增值税费
促销
服务
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数量
-+
产品名称:
128625-52-5
(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate
PYBOP
1H-苯并三唑-1-基氧三吡咯烷基六氟磷酸盐
产品介绍:

产品说明

一般描述

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (PyBOP) is an activator of carboxyl group commonly used in peptide synthesis. It also participates in the carboxylic acid esterification. It shows characteristics similar to benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and can be utilized as an alternative to BOP in peptide bond formation.

应用

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (PyBOP) may be used in the following studies:

  • As coupling reagent in the preparation strategies for peptide-oligonucleotide conjugates.
  • Synthesis of structured pure triacylglycerol (TAG) regioisomers.
  • As coupling reagent in the synthesis of a 3,5-pyrazolidinedione on soluble polyethylene glycol (PEG) polymer support.
  • Synthesis of herceptin- nanoparticles.

BOP 偶联剂类似物,不产生致癌副产物 HMPA。

法律信息

PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

线性分子式C18H28N6OP · PF6
分子量520.39
Beilstein3584612
MDL编号MFCD00077411
PubChem化学物质编号329749882
NACRESNA.22

产品性质

质量水平200
等级purum
测定≥97.0% (TLC)
reaction suitabilityreaction type: Coupling Reactions
mp~150 ℃
154-156 ℃ (dec.) (lit.)
application(s)peptide synthesis
储存温度2-8℃
SMILES stringF[P-](F)(F)(F)(F)F.C1CCN(C1)[P+](On2nnc3ccccc23)(N4CCCC4)N5CCCC5
InChI1S/C18H28N6OP.F6P/c1-2-10-18-17(9-1)19-20-24(18)25-26(21-11-3-4-12-21,22-13-5-6-14-22)23-15-7-8-16-23;1-7(2,3,4,5)6/h1-2,9-10H,3-8,11-16H2;/q+1;-1
InChI keyVIAFLMPQBHAMLI-UHFFFAOYSA-N

安全信息

象形图GHS07GHS09
警示用语:Warning
危险声明H302 - H317 - H410
预防措施声明P261 - P264 - P273 - P280 - P301 + P312 - P302 + P352
危险分类Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves

Sigma-Aldrich

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