1-[双(4-氟苯基)甲基]-4-(3-苯基-2-丙烯基)哌嗪二盐酸盐

产品名称：

30484-77-6
Flunarizine dihydrochloride
1-[Bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)piperazine dihydrochloride
氟桂嗪二盐酸盐
1-[双(4-氟苯基)甲基]-4-(3-苯基-2-丙烯基)哌嗪二盐酸盐

产品介绍：

产品说明

一般描述

Flunarizine has antihistamine, anticonvulsant and vestibular depressive properties. It protects endothelial cells from calcium overload-induced damage. Flunarizine is used to treat epilepsy, migraine prophylaxis, cerebral blood flow disturbances, peripheral vascular disease and vertigo.

应用

Flunarizine dihydrochloride has been used to study the effect of flunarizine on epileptiform activity. It is also used to study its effect on high-potassium induced increase of intracellular free calcium.

包装

1, 10 g in poly bottle

生化/生理作用

阻断 T 型 Ca²⁺/Na⁺ 通道；抑制嗜铬细胞中由 K⁺ 诱导的儿茶酚胺释放。

特点和优势

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式	C₂₆H₂₆F₂N₂ · 2HCl
分子量	477.42
Beilstein	4284243
EC 号	250-216-6
MDL编号	MFCD00058198
PubChem化学物质编号	24277835
NACRES	NA.77

产品性质

质量水平	200
测定	≥98% (TLC)
创始人	Johnson & Johnson
储存温度	2-8℃
SMILES string	Cl[H].Cl[H].Fc1ccc(cc1)C(N2CCN(CC2)C\C=C\c3ccccc3)c4ccc(F)cc4
InChI	1S/C26H26F2N2.2ClH/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21;;/h1-15,26H,16-20H2;2*1H/b7-4+;;
InChI key	RXKMOPXNWTYEHI-RDRKJGRWSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
预防措施声明	P264 - P270 - P301 + P312 - P501
危险分类	Acute Tox. 4 Oral
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

Flunarizine dihydrochloride

氟桂嗪 二盐酸盐

氟桂嗪二盐酸盐