产品说明
一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
生化/生理作用
抗肿瘤剂。通过形成自由基硝基氧灭活核糖核苷还原酶,自由基硝基氧可结合到酶活性位点的酪氨酰自由基。这可阻断脱氧核苷酸的合成,从而抑制 DNA 合成,并且诱导细胞周期同步化或 S-期细胞死亡。
包装
Unit quantity: 360 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
注意
Please find SDS provided by EDQM here..
其他说明
Sales restrictions may apply.
基本信息
线性分子式 | NH2CONHOH |
分子量 | 76.05 |
Beilstein | 1741548 |
MDL编号 | MFCD00007943 |
PubChem化学物质编号 | 329830855 |
NACRES | NA.24 |
产品性质
等级 | pharmaceutical primary standard |
manufacturer/tradename | EDQM |
application(s) | pharmaceutical (small molecule) |
格式 | neat |
储存温度 | 2-8℃ |
SMILES string | NC(=O)NO |
InChI | 1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4) |
InChI key | VSNHCAURESNICA-UHFFFAOYSA-N |
Gene Information | human ... RRM1(6240), RRM2(6241), RRM2B(50484) |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H340 - H361 |
预防措施声明 | P201 - P308 + P313 |
危险分类 | Muta. 1B - Repr. 2 |
储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich