产品说明

一般描述

A single polypeptide chain of 394 amino acids and three carbohydrate side chains linked to asparagine residues present at about 290 mg/100 ml in acute phase plasma. Serine protease inhibitor that also acts as a major physiological regulator of elastase. Inhibitor of neutrophil elastase, cathepsin G, and proteinase 3.
A single polypeptide chain of 394 amino acids and three carbohydrate side chains linked to asparagine residues. Present at about 290 mg/100 ml in acute phase plasma. Serine protease inhibitor that also acts as a major physiological regulator of elastase.

包装

1 mg in Glass bottle
5 mg in Plastic ampoule

生化/生理作用

Product does not compete with ATP.
Reversible: no
Primary Target
serine proteases
Cell permeable: no

警告

Toxicity: Standard Handling (A)

外形

Lyophilized from 300 mM NaCl, 30 mM sodium phosphate buffer, pH 6.5.

制备说明

Please refer to vial label for lot-specific volume prior to lyophilization.
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

重悬

Following reconstitution aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -70°C.

分析说明

>=75% inhibition with active-site titrated porcine trypsin using benzoyl-Arg-p-nitroanilide (Bz-Arg-pNA) as the substrate.

其他说明

Coakley, R.J., et al. 2001. Am. J. Med. Sci.321, 33.
Travis, J., and Salvesen, G.S. 1983. Annu. Rev. Biochem.52, 655.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

产品性质

安全信息