Desmosine chloride

产品名称：

10019-68-8
Desmosine chloride

产品介绍：

产品说明

一般描述

Each vial contains 1 μmole of purified desmosine.

应用

Desmosine chloride is often used in assays for free or urinary desmosine as markers for disease states characterized by elastin degradation (e.g., emphysema). Elastin degradation has shown strong correlation with vascular calcification, and pretreatment with aluminum ions can inhibit the binding of matrix metalloproteinase (MMP) to elastin.
Assays for free or urinary desmosine are often used as markers for disease states characterized by elastin degradation (e.g., emphysema). Conversely, excessive levels of incorporated desmosine are indicators of fibrotic conditions (e.g., cirrhosis).

生化/生理作用

Desmosine is a polyfunctional amino acid that forms cross-links in mature elastin.

注意

极易吸湿

分析说明

Calibrated by UV and amino acid analysis.

基本信息

经验(实验)分子式	C₂₄H₄₀ClN₅O₈
分子量	562.06
MDL编号	MFCD12910449
PubChem化学物质编号	329798901
NACRES	NA.56

产品性质

质量水平	100
生物来源	bovine
测定	99.5%±0.2%
形式	lyophilized powder
纯化方式	chromatography (and purified by solvent extraction)
储存温度	2-8℃
SMILES string	[Cl-].NC(CCCC[n+]1cc(CCC(N)C(O)=O)c(CCCC(N)C(O)=O)c(CCC(N)C(O)=O)c1)C(O)=O
InChI	1S/C24H39N5O8.ClH/c25-17(21(30)31)5-1-2-11-29-12-14(7-9-19(27)23(34)35)16(4-3-6-18(26)22(32)33)15(13-29)8-10-20(28)24(36)37;/h12-13,17-20H,1-11,25-28H2,(H3-,30,31,32,33,34,35,36,37);1H
InChI key	FUPMLZCXPJSGPV-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)