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位置:首页 > 品牌 > Sigma-Aldrich > Aprotinin, Bovine, Recombinant, Nicotiana sp., Animal-Free-CAS 9087-70-1-Calbiochem

Aprotinin, Bovine, Recombinant, Nicotiana sp., Animal-Free-CAS 9087-70-1-Calbiochem

品牌
Sigma-Aldrich
CAS
9087-70-1
货号
616371
规格纯度
recombinant, expressed in Nicotiana, heat and acid-stable competitive, reversible inhibitor of serine proteases
参考价格
1182.74 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
9087-70-1
Aprotinin, Bovine, Recombinant, Nicotiana sp., Animal-Free-CAS 9087-70-1-Calbiochem
Pancreatic Trypsin Inhibitor, Trypsin-Kallikrein Inhibitor, Kallikrein-Trypsin Inactivator, Antikrein, Basic Pancreatic Trypsin Inhibitor
产品介绍:

产品说明

一般描述

Recombinant, bovine aprotinin supplied without animal-derived components. Aprotinin is a competitive, reversible inhibitor of proteolytic and esterolytic activity. A relatively heat- and acid-stable serine protease inhibitor. Forms a tight complex, blocking the active site of the enzyme. Effective at concentrations equimolar with protease. Inhibits several proteases, including coagulation factors in the prephase of blood clotting, tissue and leukocytic proteinases, chymotrypsin, trypsin (Kd = 5 x 10-14 M), plasmin (Kd = 2.3 x 10-10 M), and kallikrein (Kd = 1 x 10-7 M). Proteases not inhibited by aprotinin include Factor Xa, thrombin, pepsin, papain, and carboxypeptidases A and B. Useful for protein purification and for extending the life of cells in culture by preventing proteolytic damage.

包装

25 mg in Glass bottle
1, 5 mg in Plastic ampoule
Please refer to vial label for lot-specific concentration.

生化/生理作用

Product does not compete with ATP.
Reversible: yes
Kd = 5 x 10-14 M, 2.3 x 10-10 M, 1 x 10-7 M against trypsin, plasmin, and kallikrein, respectively
Primary Target
chymotrypsin
Cell permeable: no

警告

Toxicity: Standard Handling (A)

单位定义

One TIU (Trypsin Inhibitory Unit) is defined as the amount of aprotinin or product or inhibitor that will decrease the activity of 2 trypsin units by 50% where one trypsin unit will hydrolyze 1 µmol BAPNA per min at 25°C, pH 7.8.

外形

Contains no animal-derived components.

其他说明

Deutscher, M.P., 1990. Methods Enzymol.182, 83.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C284H432N84O79S7
分子量6511.44
MDL编号MFCD00130541
EC索引号2329949

产品性质

质量水平200
重组expressed in Nicotiana
测定≥95% (SDS-PAGE)
形式powder
specific activity>5 TIU/mg protein
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
颜色 white to yellow
运输wet ice
储存温度2-8℃

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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