(<I>R</I>)-3-氨基-1-叔丁氧羰基哌啶

产品名称：

188111-79-7
(R)-(-)-3-Amino-1-Boc-piperidine
(R)-1-Boc-3-piperidinamine
tert-Butyl (R)-3-amino-1-piperidinecarboxylate
(R)-3-氨基-1-叔丁氧羰基哌啶
(R)-1-Boc-3-氨基哌啶
(R)-1-叔丁氧羰基-3-氨基哌啶

产品介绍：

产品说明

一般描述

(R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents.

应用

(R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor.

基本信息

经验(实验)分子式	C₁₀H₂₀N₂O₂
分子量	200.28
MDL编号	MFCD03094717
PubChem化学物质编号	329748523
NACRES	NA.22

产品性质

质量水平	100
测定	≥98.0% (TLC)
旋光性	[α]/D -28.5±2°, c = 1 in DMF
SMILES string	CC(C)(C)OC(=O)N1CCC[C@@H](N)C1
InChI	1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1
InChI key	AKQXKEBCONUWCL-MRVPVSSYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H315 - H319 - H335
预防措施声明	P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类	Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	10 - Combustible liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter