产品说明
一般描述
Fmoc-Asn(Trt)-OH has good solubility properties in most organic solvents, and its use has been shown to result in significantly purer peptides than other derivatives used for the introduction of Asn [1, 2]. Coupling can be performed by standard procedures. The trityl group is normally removed by 95% TFA in 1-3 hours, with no alkylation of Trp residues. When Asn(Trt) is the N-terminal residue, the reaction time may need to be extended to ensure complete deprotection [3].
应用
Fmoc-Asn(Trt)-OH has been used to synthesize peptides on cellulose membrane by SPOT method
包装
5, 25, 100 g in poly bottle
1 kg in poly bottle
基本信息
| 经验(实验)分子式 | C38H32N2O5 |
| 分子量 | 596.67 |
| Beilstein | 4343823 |
| MDL编号 | MFCD00077049 |
| eCl@ss | 32160406 |
| PubChem化学物质编号 | 57651076 |
| NACRES | NA.26 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥97.0% |
| 旋光性 | [α]20/D −15.0±1°, c = 1% in methanol |
| reaction suitability | reaction type: Fmoc solid-phase peptide synthesis |
| mp | 201-204 ℃ (lit.) |
| application(s) | peptide synthesis |
| 官能团 | Fmoc |
| 储存温度 | 2-8℃ |
| SMILES string | OC(=O)[C@H](CC(=O)NC(c1ccccc1)(c2ccccc2)c3ccccc3)NC(=O)OCC4c5ccccc5-c6ccccc46 |
| InChI | 1S/C38H32N2O5/c41-35(40-38(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28)24-34(36(42)43)39-37(44)45-25-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33/h1-23,33-34H,24-25H2,(H,39,44)(H,40,41)(H,42,43)/t34-/m0/s1 |
| InChI key | KJYAFJQCGPUXJY-UMSFTDKQSA-N |
安全信息
| 象形图 |  |
| 危险声明 | H411 |
| 危险分类 | Aquatic Chronic 2 |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
