产品说明
应用
5-AIQ hydrochloride is an inhibitor of poly (ADP-ribose) polymerase-1 (PARP-1). 5-AIQ hydrochloride was used in a study that determined PARP inhibitors have antiangiogenic effects, which may have tremendous clinical implications for the treatment of various cancers and certain retinopathies.
包装
1, 5 mg in glass bottle
生化/生理作用
5-AIQ hydrochloride is an inhibitor of poly (ADP-ribose) polymerase-1 (PARP-1).
基本信息
经验(实验)分子式 | C9H9ClN2O |
分子量 | 196.63 |
MDL编号 | MFCD03452659 |
PubChem化学物质编号 | 24724396 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥97% (HPLC) |
形式 | solid |
颜色 | tan |
溶解性 | DMSO: >20 mg/mL H2O: >20 mg/mL |
储存温度 | −20℃ |
SMILES string | Cl[H].Nc1cccc2C(=O)NC=Cc12 |
InChI | 1S/C9H8N2O.ClH/c10-8-3-1-2-7-6(8)4-5-11-9(7)12;/h1-5H,10H2,(H,11,12);1H |
InChI key | KWNLARCFSYAXLT-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H315 - H319 - H335 |
预防措施声明 | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
靶器官 | Respiratory system |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich