产品说明
生化/生理作用
Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid. Diglycine is known to catalyze the formation of homo- and hetero dipeptides more efficiently than glycine.
基本信息
线性分子式 | NH2CH2CONHCH2COOH |
分子量 | 132.12 |
Beilstein | 1765223 |
EC 号 | 209-127-8 |
MDL编号 | MFCD00008130 |
PubChem化学物质编号 | 329757576 |
NACRES | NA.25 |
产品性质
质量水平 | 200 |
产品线 | BioXtra |
测定 | ≥99.0% (NT) |
形式 | powder |
technique(s) | ligand binding assay: suitable |
灼烧残渣 | ≤0.1% (as SO4) |
缺失 | ≤1% loss on drying, 110 ℃ |
颜色 | white |
有效pH范围 | 7.5 - 8.9 |
pKa (25 ℃) | 8.2 |
mp | 220-240 ℃ (dec.) |
溶解性 | H2O: 1 M at 20 ℃, clear, colorless |
痕量阴离子 | chloride (Cl-): ≤50 mg/kg sulfate (SO42-): ≤50 mg/kg |
痕量阳离子 | Ca: ≤10 mg/kg Cd: ≤5 mg/kg Co: ≤5 mg/kg Cr: ≤5 mg/kg Cu: ≤5 mg/kg Fe: ≤5 mg/kg K: ≤50 mg/kg Mg: ≤5 mg/kg Mn: ≤5 mg/kg Na: ≤50 mg/kg Ni: ≤5 mg/kg Pb: ≤5 mg/kg Zn: ≤5 mg/kg |
SMILES string | NCC(=O)NCC(O)=O |
InChI | 1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9) |
InChI key | YMAWOPBAYDPSLA-UHFFFAOYSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich