产品说明
应用
Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells . It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro .
包装
50 mg in glass insert
1 g in glass bottle
生化/生理作用
Anticancer activity for chrysophanic acid is via the EGFR/mTOR mediated signaling transduction pathway . Chrysophanic acid has two hydrophobic positions on the molecule (C-6 and the methyl group attached to C-3) which are responsible for the compound′s activity against poliovirus .
其他说明
Keep container tightly closed in a dry and well-ventilated place.
基本信息
| 经验(实验)分子式 | C15H10O4 |
| 分子量 | 254.24 |
| Beilstein | 1252300 |
| EC 号 | 207-572-2 |
| MDL编号 | MFCD00001208 |
| PubChem化学物质编号 | 57648009 |
| NACRES | NA.85 |
产品性质
| 质量水平 | 100 |
| 测定 | 98% |
| 形式 | crystalline |
| 颜色 | yellow-orange |
| 溶解性 | chloroform: 1% |
| 作用机制 | enzyme | inhibits |
| 抗生素抗菌谱 | neoplastics viruses |
| SMILES string | Cc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1 |
| InChI | 1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3 |
| InChI key | LQGUBLBATBMXHT-UHFFFAOYSA-N |
| Gene Information | human ... ELA2(1991) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 - H335 |
| 预防措施声明 | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich
m.cnreagent.com
